• Global Healthcare Medical GHM CM-400 US - Fully automated closed-system clinical chemistry analyzer with 400 T/H constant throughput, 90 sample positions, 80 reagent positions (40 outer + 40 inner), 90 glass reaction cuvettes, direct solid heating at (37.0 ± 0.2)°C, 8-step warm liquid washing, and diffraction grating optics for medium-to-high volume clinical laboratories
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Global Healthcare Medical

GHM CM-400 US – Closed-System Clinical Chemistry Analyzer with 400 T/H Constant Throughput, 90 Sample Positions, and 8-Step Warm Liquid Washing

GHM CM-400 US – Closed-System Clinical Chemistry Analyzer with 400 T/H Constant Throughput, 90 Sample Positions, and 8-Step Warm Liquid Washing

$14,999.00
$20,000.00 $14,999.00
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SKU: GHM CM-400 US
Brand: Global Healthcare Medical

Global Healthcare Medical GHM CM-400 US is a fully automated, closed-system clinical chemistry analyzer engineered for hospital laboratories, diagnostic centers, and academic research institutes. Delivering a constant photometric throughput of 400 tests per hour (with an optional ISE module adding 400 T/H), the system pairs high-efficiency sample processing with a direct solid-heating thermostatic system and intelligent online reagent loading—a reliable benchtop-scale solution for laboratories processing substantial daily workloads without compromising analytical quality.

The closed-system architecture pairs the instrument exclusively with the manufacturer's dedicated reagent, calibrator, and control portfolio. Reagent formulations, onboard stability profiles, and application parameters are matched to the analyzer from the outset, eliminating the variability introduced by third-party reagent compatibility. This design supports consistent quality control, lot-to-lot traceability, and reproducible results across the entire testing menu—a critical advantage for laboratories prioritizing analytical standardization and regulatory compliance. Closed-system operation also delivers a plug-and-play workflow with automatic barcode-based reagent recognition, reducing hands-on setup time for laboratory staff.

The analyzer features 80 reagent positions (40 outer + 40 inner) supporting simultaneous testing of up to 78 chemistry items, 90 sample positions (30 outer + 30 median + 30 inner for calibrators and controls), and 90 glass reaction cuvettes with permanent use options. The 8-step warm liquid washing system employs whole-probe stereo cleaning technology, achieving a cross-contamination rate below 0.01% (or <0.05% per alternative specification). The optical system utilizes a diffraction grating with 16 wavelengths, and the system supports serum, plasma, whole blood, urine, and cerebrospinal fluid sample types.

Key Features & Benefits

Closed-System Architecture – Dedicated Reagent Integration for Consistent Results

The GHM CM-400 US operates as a dedicated closed-system analyzer, designed to run exclusively with the manufacturer's matched reagent, calibrator, and control portfolio. This integrated approach ensures that reagent application parameters—wavelength, sample-to-reagent ratio, incubation timing, and calibration algorithms—are pre-validated and locked to the instrument. The result is greater analytical consistency, reduced operator-dependent variability, and simplified quality management compared to open-system alternatives where third-party reagent compatibility must be verified in-house.



Feature Benefit
Dedicated reagent ecosystem Reagents, calibrators, and controls are purpose-matched to the analyzer
Pre-validated application parameters No manual programming of third-party reagent protocols
Lot-to-lot traceability Supported through the closed reagent supply chain
Simplified QC and calibration Consistent performance from a unified diagnostic system
Plug-and-play workflow Automatic barcode-based reagent recognition for fast setup

High-Efficiency Sample Processing – 400 T/H Constant Throughput

A constant photometric throughput of 400 T/H—with an optional ISE module adding 400 T/H—supports busy clinical laboratories processing substantial daily workloads. The system accommodates 90 sample positions and 80 reagent positions, enabling broad on-board menu coverage with up to 78 items tested simultaneously.



Feature Benefit
400 T/H (photometric) High-volume processing for medium-to-large laboratories
400 T/H (ISE, optional) Dedicated electrolyte throughput
90 sample positions High sample loading capacity (30 outer + 30 median + 30 inner)
80 reagent positions (40 outer + 40 inner) Extensive on-board menu coverage
Up to 78 simultaneous items Broad testing without reagent changes

Dry Heating Thermostatic System – 37 ± 0.2°C Precision

The direct solid-heating system enables faster heating and reduces pre-heating time compared to water-bath alternatives. The thermostatic system maintains the reaction solution in the cuvettes at (37.0 ± 0.2)°C, supporting consistent enzyme and substrate kinetics across all assays.



Feature Benefit
Direct solid heating Faster warm-up and reduced pre-heating time
(37.0 ± 0.2)°C Stable reaction environment for reliable kinetics
Maintenance-free design Reduced operational complexity

Accurate Sampling System – Polished Probes with Multi-Layer Detection

Internally and externally polished sampling probes, combined with high-precision liquid volume tracking and level detection, ensure accurate aspiration across the full sample and reagent volume range. Bubble detection and probe-clot (clogging) detection further safeguard sampling integrity, while an optional water-quality monitoring module and built-in degassing unit support consistent fluid handling.



Feature Benefit
Polished sampling probes Reduced sample adhesion and carryover
Liquid volume tracking & level detection Accurate aspiration and reagent management
Bubble detection Prevents inaccurate results from air bubbles
Probe-clot (clogging) detection Automated alerts for probe obstructions
Optional water-quality monitoring Additional layer of fluid integrity assurance
Built-in degassing unit Supports consistent reagent and sample handling
Minimum sample volume: 1.5 µL Low sample consumption

8-Step Warm Liquid Washing – Cross-Contamination < 0.01%

The 8-step warm liquid washing system employs whole-probe stereo cleaning technology, achieving a cross-contamination rate below 0.01% (or <0.05% per alternative specification). The washing sequence includes pure water washing (steps 1, 4-6), cleaning solution washing (steps 2-3), and wiping module washing (steps 7-8). An anti-overflow function prevents liquid spillage during the washing cycle, further safeguarding analytical integrity.



Feature Benefit
8-step warm liquid washing Thorough cleaning between every test
Whole-probe stereo cleaning Enhanced probe hygiene
Cross-contamination < 0.01% Minimal carryover for reliable results
Anti-overflow function Prevents liquid spillage during washing

Intelligent Online Loading System – Reagents Loaded During Testing

Reagents can be loaded on-board during an active test run, reducing downtime between reagent changes and supporting continuous workflow in high-volume laboratories. The Peltier cooling system provides a longer maintenance period and reduces repair probability.



Feature Benefit
On-board reagent loading during testing Reduced downtime between reagent changes
Continuous workflow Higher effective instrument utilization
Peltier cooling system Extended maintenance intervals and reduced repair probability

Advanced Optical System – Diffraction Grating, 16 Wavelengths

The optical system features a diffraction grating and 16 wavelengths for broad assay compatibility. 90 glass reaction cuvettes with permanent use options reduce consumable costs over the instrument's service life. Multi-point calibration curves (up to 7 points) and automatic pre-dilution support extended analytical measurement ranges.



Feature Benefit
Diffraction grating, 16 wavelengths Broad assay compatibility
Glass reaction cuvettes Permanent-use option available; reduced consumable costs
Multi-point calibration (up to 7 points) Enhanced curve fitting accuracy
Automatic pre-dilution Extended analytical measurement range
Latex immunoturbidimetry, immunoturbidimetry, colorimetry Multiple detection principles

Flexible Specimen Handling

The system accepts serum, plasma, whole blood, urine, and cerebrospinal fluid, accommodating diverse clinical workflows from routine screening to specialized assays.



Feature Benefit
Serum / plasma / whole blood / urine / CSF Flexible specimen handling across clinical applications
90 sample positions (incl. calibrators & controls) Consolidated sample and QC loading
Water consumption: ≤ 15 L/hour Economical purified water usage

Reagent, Calibrator, Control & Consumable Pricing (EXW, USD)

The GHM CM-400 US closed system operates with a dedicated reagent and consumable portfolio. Below is the complete pricing schedule, expressed in USD. All prices are EXW per kit unless otherwise indicated.

Liver Function



Product Packing Total Volume (mL) Tests/Kit EXW Price (USD/kit) EXW Price (USD/test)
TBA R1: 4×45 mL, R2: 4×15 mL 240 970 86.40 0.1336
AFU 2×50 mL 100 420 45.00 0.1607
ALT R1: 4×40 mL, R2: 4×20 mL 240 980 10.80 0.0165
AST R1: 4×40 mL, R2: 4×20 mL 240 980 10.80 0.0165
ALP R1: 4×40 mL, R2: 2×20 mL 200 710 10.50 0.0222
GGT R1: 4×40 mL, R2: 2×20 mL 200 710 12.00 0.0254
TP 6×50 mL 300 1580 6.75 0.0064
ALB 6×50 mL 300 1320 6.75 0.0077
TB R1: 4×40 mL, R2: 2×20 mL 200 710 9.00 0.0190
DB R1: 4×40 mL, R2: 2×20 mL 200 710 9.00 0.0190
PA R1: 1×45 mL, R2: 1×15 mL 60 240 16.20 0.1013
CHE R1: 4×40 mL, R2: 2×20 mL 200 650 21.00 0.0485
ADA R1: 2×40 mL, R2: 2×20 mL 120 400 36.00 0.1350
5′-NT R1: 2×40 mL, R2: 2×20 mL 120 400 45.00 0.1688
MAO 2×50 mL 100 520 18.00 0.0519
GLDH R1: 2×60 mL, R2: 2×20 mL 160 670 28.80 0.0645
LAP R1: 2×60 mL, R2: 2×20 mL 160 670 28.80 0.0645
CG R1: 2×30 mL, R2: 1×20 mL 80 320 102.00 0.4781
AMM R1: 2×55 mL, R2: 2×20 mL 150 650 49.50 0.1142
GR R1: 2×55 mL, R2: 2×20 mL 150 650 135.00 0.3115
GPDA R1: 2×60 mL, R2: 2×20 mL 160 670 72.00 0.1612

Myocardial Enzyme



Product Packing Total Volume (mL) Tests/Kit EXW Price (USD/kit) EXW Price (USD/test)
LDH R1: 4×40 mL, R2: 4×20 mL 240 980 14.40 0.0220
CK R1: 4×40 mL, R2: 2×20 mL 200 710 45.00 0.0951
CK-MB (Immunoinhibition) R1: 2×48 mL, R2: 2×12 mL 120 420 72.00 0.2571
HBDH R1: 4×40 mL, R2: 4×20 mL 240 980 16.20 0.0248
LDH1 R1: 2×60 mL, R2: 2×20 mL 160 670 28.80 0.0645
CK-MB (Immunoturbidimetric) R1: 2×55 mL, R2: 2×20 mL 150 650 337.50 0.7788

Renal Function



Product Packing Total Volume (mL) Tests/Kit EXW Price (USD/kit) EXW Price (USD/test)
CRE-E R1: 4×45 mL, R2: 4×15 mL 240 1000 72.00 0.1080
BUN R1: 4×40 mL, R2: 2×20 mL 200 710 10.50 0.0222
UA R1: 4×40 mL, R2: 4×20 mL 240 980 12.60 0.0193
β2-MG R1: 2×40 mL, R2: 2×10 mL 100 350 75.00 0.3214
CysC R1: 2×40 mL, R2: 2×10 mL 100 350 75.00 0.3214
NAG R1: 2×60 mL, R2: 2×20 mL 160 670 48.00 0.1075

Glucose Metabolism



Product Packing Total Volume (mL) Tests/Kit EXW Price (USD/kit) EXW Price (USD/test)
GLU-HK R1: 4×40 mL, R2: 4×20 mL 240 980 14.40 0.0220
GLU-OX R1: 4×40 mL, R2: 4×20 mL 240 980 10.08 0.0154
FMN R1: 4×40 mL, R2: 2×20 mL 200 710 30.00 0.0634
D3-H R1: 2×40 mL, R1a: 2×5 mL, R2: 2×15 mL 120 480 54.00 0.1688
HbA1c R1: 2×15 mL, R2a: 1×0.5 mL, R2b: 1×9.5 mL, Hemolyse: 2×50 mL 40 148 42.00 0.4257
LAC 4×50 mL 200 1050 48.00 0.0686
GA R1: 2×30 mL, R2: 1×15 mL 75 265 180.00 1.0189
NEFA R1: 2×30 mL, R2: 1×15 mL 75 240 78.75 0.4922
SA R1: 2×30 mL, R2: 1×20 mL 80 340 60.00 0.2647

Blood Lipids & Cardiovascular



Product Packing Total Volume (mL) Tests/Kit EXW Price (USD/kit) EXW Price (USD/test)
TG R1: 4×40 mL, R2: 4×20 mL 240 980 23.40 0.0358
TCH R1: 4×40 mL, R2: 4×20 mL 240 980 14.40 0.0220
HDL-C R1: 4×45 mL, R2: 4×15 mL 240 770 54.00 0.1052
LDL-C R1: 4×45 mL, R2: 4×15 mL 240 770 72.00 0.1403
ApoA1 R1: 1×45 mL, R2: 1×15 mL 60 165 18.00 0.1636
ApoB R1: 1×45 mL, R2: 1×15 mL 60 230 18.00 0.1174
ApoE R1: 1×45 mL, R2: 1×15 mL 60 240 54.00 0.3375
Lp(a) R1: 4×40 mL, R2: 2×20 mL 240 710 216.00 0.4563
HCY R1: 2×30 mL, R2: 1×9 mL 69 170 103.50 0.9132
ACE 2×50 mL 100 410 45.00 0.1646
Lp-PLA2 R1: 1×60 mL, R2a: 1×14.25 mL, R2b: 1×0.75 mL 75 230 225.00 1.4674
Myo R1: 2×55 mL, R2: 2×20 mL 150 670 225.00 0.5037

Trace Elements & Electrolytes



Product Packing Total Volume (mL) Tests/Kit EXW Price (USD/kit) EXW Price (USD/test)
Ca 4×45 mL 180 780 6.75 0.0130
Mg 4×45 mL 180 940 7.56 0.0121
P R1: 4×40 mL, R2: 4×20 mL 240 980 7.20 0.0110
CO2 5×20 mL 100 490 27.00 0.0827
Fe R1: 2×40 mL, R2: 2×20 mL 120 480 11.70 0.0366
Na R1: 2×60 mL, R2: 2×20 mL 160 670 48.00 0.1075
K R1: 2×60 mL, R2: 2×20 mL 160 670 96.00 0.2149
Cl 5×40 mL 200 1040 7.50 0.0108
UIBC R1: 2×60 mL, R2: 2×12 mL 144 360 17.28 0.0720

Specific Protein & Rheumatism



Product Packing Total Volume (mL) Tests/Kit EXW Price (USD/kit) EXW Price (USD/test)
ASO R1: 2×40 mL, R2: 2×10 mL 100 350 82.50 0.3536
RF R1: 2×40 mL, R2: 2×10 mL 100 350 75.00 0.3214
CRP (Immunoturbidimetric) R1: 12×12.9 mL, R2: 12×12.9 mL 309.6 920 162.54 0.2650
CRP (Latex-enhanced Immunoturbidimetric) R1: 12×12.9 mL, R2: 12×12.9 mL 309.6 920 255.42 0.4164
mAlb R1: 2×40 mL, R2: 2×10 mL 100 410 39.00 0.1427
CSF 2×50 mL 100 520 13.50 0.0389
RBP R1: 1×45 mL, R2: 1×15 mL 60 210 63.00 0.4500
C3 R1: 1×45 mL, R2: 1×15 mL 60 240 16.20 0.1013
C4 R1: 1×45 mL, R2: 1×15 mL 60 240 16.20 0.1013
IgA R1: 1×45 mL, R2: 1×15 mL 60 230 22.50 0.1467
IgM R1: 1×45 mL, R2: 1×15 mL 60 240 18.00 0.1125
IgG R1: 1×45 mL, R2: 1×15 mL 60 230 20.25 0.1321
PG I R1: 2×30 mL, R2: 2×6 mL 72 170 216.00 1.9059
PG II R1: 2×30 mL, R2: 2×6 mL 72 170 216.00 1.9059
CCP R1: 2×30 mL, R2: 1×20 mL 80 320 360.00 1.6875
Fer R1: 2×60 mL, R2: 1×60 mL 180 720 486.00 1.0125
TRF R1: 2×55 mL, R2: 2×20 mL 150 650 67.50 0.1558
Hs-CRP R1: 2×60 mL, R2: 1×60 mL 180 740 148.50 0.3010

Pancreatitis



Product Packing Total Volume (mL) Tests/Kit EXW Price (USD/kit) EXW Price (USD/test)
AMY R1: 4×40 mL, R2: 2×20 mL 200 950 84.00 0.1326
Lps R1: 2×40 mL, R2: 2×20 mL 120 480 90.00 0.2813

Venous Thromboembolism & Coagulation



Product Packing Total Volume (mL) Tests/Kit EXW Price (USD/kit) EXW Price (USD/test)
D-Dimer R1: 1×45 mL, R2: 1×15 mL 60 240 162.00 1.0125

Cleaning Solutions



Product Packing Total Volume EXW Price (USD) Note
Cleaning Solution 1×2 L 2 L 27.00 Six months for 800 tests
Acidic Cleaning Solution 2×60 mL 120 mL 22.50 One month
Alkaline Cleaning Solution 2×60 mL 120 mL 22.50 One month

Calibrators



Product Packing EXW Price (USD)
Single-test Calibrator / 7.50
Composite Calibrator Serum (ALT, AST, ALB, TB, ALP, CHE, GGT, BUN, CRE-E, UA, LDH, CK, HBDH, TG, GLU-HK, GLU-OX, AMY, LAP, GDH, Apo A1, Apo B, D3-H, IgA, IgM, IgG, UIBC) 1×3 mL 12.00
Lipid Compound Calibrator (HDL-C, LDL-C, TG, TCH) 1×1 mL 10.50

Controls



Product Packing EXW Price (USD)
Single-test Control / 7.50
Composite Quality Control Serum (ALT, AST, ALB, TB, ALP, CHE, GGT, BUN, CRE-E, UA, LDH, CK, HBDH, TG, GLU-HK, GLU-OX, AMY, LAP, GDH, Apo A1, Apo B, D3-H, IgA, IgM, IgG, UIBC) 1×3 mL 12.00
Lipid Compound Control (HDL-C, LDL-C, TG, TCH, Apo A1, Apo B) 1×1 mL 10.50

Spare Parts & Optional ISE Module



Product Description EXW Price (USD) Note
Computer / 900.00 For CM400 & CM800
ISE Module (for CM 400, 480 & 800) ISE Module 3,450.00 /
Na+ Electrodes 300.00 /
K+ Electrodes 300.00 /
Cl- Electrodes 300.00 /
Li+ Electrodes 345.00 /
Reference Electrode 300.00 /
Na+/K+/Cl-/Li+ Reagents 330.00 1800 tests for each
ISE Control 150.00 3×1 level×10 mL
ISE Module Cleaning Solution 105.00 90 mL

Product Specifications



Specification Detail
Model / SKU GHM CM-400 US
Product Type Fully Automated Closed-System Clinical Chemistry Analyzer
Intended Use Quantitative determination of biochemical parameters in serum, plasma, whole blood, urine, and cerebrospinal fluid; professional in vitro diagnostic use
System Configuration Closed system; dedicated reagent, calibrator, and control portfolio
Throughput Constant 400 T/H (photometric); optional ISE module 400 T/H
Test Principles Latex immunoturbidimetry, immunoturbidimetry, colorimetry
Test Methods Rate method, end point method, fixed-time method
Sample Tray 90 positions (30 outer + 30 median + 30 inner for calibrators/controls)
Reagent Tray 80 positions (40 outer + 40 inner); Peltier cooling
Simultaneous Test Items Up to 78 chemistry items
Cuvettes 90 glass reaction cuvettes (quartz, 5×5 mm); permanent use option
Reaction Temperature Direct solid heating, (37.0 ± 0.2)°C constant temperature control
Washing System 8-step warm liquid washing; whole-probe stereo cleaning
Cross-Contamination Rate < 0.01% (or <0.05% per alternative specification)
Sample Volume 1.50–50.0 µL (0.1 µL increment)
Reagent Volume R1: 10.0–450.0 µL; R2/R3/R4: 0 or 10.0–450.0 µL
Reaction Volume 100.0–360.0 µL
Minimum Sampling Volume 1.5 µL
Sample Types Serum, plasma, whole blood, urine, cerebrospinal fluid
Optical System Diffraction grating; 16 wavelengths; 20 W halogen lamp (>2000 h); photodiode array detector
Calibration Multi-point calibration curve (up to 7 points)
Dilution Automatic pre-dilution
Water Consumption ≤ 15 L purified water per hour
Dimensions 1160 mm (L) × 790 mm (W) × 1140 mm (H)
Gross Weight 300 kg
Regulatory Status Manufactured under EN ISO 13485 certified quality management system

Why Clinical Laboratories Choose Global Healthcare Medical



Consideration GHM CM-400 US
Closed-system architecture Dedicated reagent ecosystem for consistent, traceable results
High throughput Constant 400 T/H photometric; optional 400 T/H ISE
Extensive capacity 90 sample positions; 80 reagent positions; up to 78 simultaneous items
Direct solid heating (37.0 ± 0.2)°C precision without water bath maintenance
Multi-layer sampling safeguards Polished probes, bubble detection, probe-clot detection
8-step warm washing Cross-contamination < 0.01% (or <0.05%)
Intelligent online loading Reagents loaded during testing to reduce downtime
Advanced optics Diffraction grating, 16 wavelengths
Peltier cooling system Extended maintenance intervals
ISO 13485 certified Quality management system compliance

About Global Healthcare Medical

Global Healthcare Medical is dedicated to connecting clinical laboratories and diagnostic centers with high-performance analytical systems designed for reliable operation in demanding healthcare environments. The GHM CM-400 US is part of our professional clinical chemistry line, developed to support accurate, efficient, and scalable testing in medium-to-high volume laboratory settings.

Our focus is on dependable analytical performance, clear documentation, and responsive support for professional clinical operations.

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