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Global Healthcare Medical
GHM CM-430 US – Open-System Clinical Chemistry Analyzer with 400 T/H Throughput, 90 Sample Positions, and 8-Step Warm Liquid Washing
GHM CM-430 US – Open-System Clinical Chemistry Analyzer with 400 T/H Throughput, 90 Sample Positions, and 8-Step Warm Liquid Washing
SKU: GHM CM-430 US
Brand: Global Healthcare Medical
Global Healthcare Medical GHM CM-430 US is a fully automated, open-system clinical chemistry analyzer engineered for hospital laboratories, diagnostic centers, and academic research institutes. Delivering a constant photometric throughput of 400 tests per hour (with an optional ISE module adding 400 T/H), the system pairs high-efficiency sample processing with a direct dry-heating thermostatic system and intelligent online reagent loading—a reliable benchtop-scale solution for laboratories processing substantial daily workloads without compromising analytical quality.
The open-system configuration allows laboratory staff to program assay parameters for third-party reagents or in-house prepared chemistries alongside the manufacturer's portfolio. This eliminates vendor lock-in, enables competitive reagent sourcing, and allows the testing menu to adapt as clinical requirements evolve.
The analyzer features 80 reagent positions supporting simultaneous testing of up to 78 chemistry items, 90 sample positions accommodating patient samples, calibrators, and controls, and glass reaction cuvettes with permanent use options. The 8-step warm liquid washing system employs whole-probe stereo cleaning technology, achieving a cross-contamination rate below 0.01%. The optical system utilizes a diffraction grating with 16 wavelengths, and the system supports serum, plasma, whole blood, urine, and cerebrospinal fluid sample types.
Key Features & Benefits
Open-System Flexibility – Program Third-Party and In-House Reagents
The GHM CM-430 US operates as a true open-system analyzer, allowing laboratory staff to program assay parameters for third-party reagents or in-house prepared chemistries. This eliminates vendor lock-in, enables competitive reagent sourcing, and allows the testing menu to adapt as clinical needs evolve—all while maintaining the high-throughput performance of a dedicated automated platform.
| Feature | Benefit |
|---|---|
| Open reagent system | Freedom to use third-party or in-house reagents |
| User-programmable parameters | Adaptable to evolving testing requirements |
| Vendor-independent sourcing | Potential for reduced cost-per-test |
| No proprietary lock-in | Long-term operational flexibility |
High-Efficiency Sample Processing – 400 T/H Constant Throughput
A constant photometric throughput of 400 T/H—with an optional ISE module adding 400 T/H—supports busy clinical laboratories processing substantial daily workloads. The system accommodates 90 sample positions and 80 reagent positions, enabling broad on-board menu coverage with up to 78 items tested simultaneously.
| Feature | Benefit |
|---|---|
| 400 T/H (photometric) | High-volume processing for medium-to-large laboratories |
| 400 T/H (ISE, optional) | Dedicated electrolyte throughput |
| 90 sample positions | High sample loading capacity |
| 80 reagent positions | Extensive on-board menu coverage |
| Up to 78 simultaneous items | Broad testing without reagent changes |
Dry Heating Thermostatic System – 37 ± 0.2°C Precision
The direct dry-heating system enables faster heating and reduces pre-heating time compared to water-bath alternatives. The thermostatic system maintains the reaction solution in the cuvettes at (37.0 ± 0.2)°C, supporting consistent enzyme and substrate kinetics across all assays.
| Feature | Benefit |
|---|---|
| Direct dry heating | Faster warm-up and reduced pre-heating time |
| (37.0 ± 0.2)°C | Stable reaction environment for reliable kinetics |
| Maintenance-free design | Reduced operational complexity |
Accurate Sampling System – Multi-Layer Detection & Fluid Integrity
Internally and externally polished sampling probes, combined with high-precision liquid volume tracking and level detection, ensure accurate aspiration across the full sample and reagent volume range. Bubble detection and probe-clot (clogging) detection further safeguard sampling integrity, while an optional water-quality monitoring module and built-in degassing unit support consistent fluid handling.
| Feature | Benefit |
|---|---|
| Polished sampling probes | Reduced sample adhesion and carryover |
| Liquid volume tracking & level detection | Accurate aspiration and reagent management |
| Bubble detection | Prevents inaccurate results from air bubbles |
| Probe-clot (clogging) detection | Automated alerts for probe obstructions |
| Optional water-quality monitoring | Additional layer of fluid integrity assurance |
| Built-in degassing unit | Supports consistent reagent and sample handling |
| Minimum sample volume: 1.5 µL | Low sample consumption |
8-Step Warm Liquid Washing – Cross-Contamination < 0.01%
The 8-step warm liquid washing system employs whole-probe stereo cleaning technology, achieving a cross-contamination rate below 0.01%. An anti-overflow function prevents liquid spillage during the washing cycle, further safeguarding analytical integrity.
| Feature | Benefit |
|---|---|
| 8-step warm liquid washing | Thorough cleaning between every test |
| Whole-probe stereo cleaning | Enhanced probe hygiene |
| Cross-contamination < 0.01% | Minimal carryover for reliable results |
| Anti-overflow function | Prevents liquid spillage during washing |
Intelligent Online Loading & Peltier Cooling System
Reagents can be loaded on-board during an active test run, reducing downtime between reagent changes and supporting continuous workflow. The Peltier cooling system provides a longer maintenance period and reduces repair probability.
| Feature | Benefit |
|---|---|
| On-board reagent loading during testing | Reduced downtime between reagent changes |
| Continuous workflow | Higher effective instrument utilization |
| Peltier cooling system | Extended maintenance intervals and reduced repair probability |
Advanced Optical System & Cost-Effective Mechanics
The optical system features a diffraction grating and 16 wavelengths for broad assay compatibility. Glass reaction cuvettes with permanent use options reduce consumable costs over the instrument's service life. An upgraded mechanical design with one stirrer less reduces maintenance requirements while maintaining mixing performance.
| Feature | Benefit |
|---|---|
| Diffraction grating, 16 wavelengths | Broad assay compatibility |
| Glass reaction cuvettes (permanent use) | Reduced consumable costs |
| Upgraded mechanics (one stirrer less) | Lower maintenance requirements |
| Multi-point calibration (up to 7 points) | Enhanced curve fitting accuracy |
| Automatic pre-dilution | Extended analytical measurement range |
Flexible Specimen Handling
The system accepts serum, plasma, whole blood, urine, and cerebrospinal fluid, accommodating diverse clinical workflows from routine screening to specialized assays.
| Feature | Benefit |
|---|---|
| Serum / plasma / whole blood / urine / CSF | Flexible specimen handling across clinical applications |
| 90 sample positions (incl. calibrators & controls) | Consolidated sample and QC loading |
| Water consumption: ≤ 15 L/hour | Economical purified water usage |
Reagent, Calibrator, Control & Consumable Pricing (EXW, USD)
The GHM CM-430 US open system operates with a comprehensive reagent and consumable portfolio. Below is the complete pricing schedule, expressed in USD. All prices are EXW per kit unless otherwise indicated.
Liver Function
| Product | Packing | Total Volume (mL) | Tests/Kit | EXW Price (USD/kit) | EXW Price (USD/test) |
|---|---|---|---|---|---|
| TBA | R1: 4×45 mL, R2: 4×15 mL | 240 | 970 | 86.40 | 0.1336 |
| AFU | 2×50 mL | 100 | 420 | 45.00 | 0.1607 |
| ALT | R1: 4×40 mL, R2: 4×20 mL | 240 | 980 | 10.80 | 0.0165 |
| AST | R1: 4×40 mL, R2: 4×20 mL | 240 | 980 | 10.80 | 0.0165 |
| ALP | R1: 4×40 mL, R2: 2×20 mL | 200 | 710 | 10.50 | 0.0222 |
| GGT | R1: 4×40 mL, R2: 2×20 mL | 200 | 710 | 12.00 | 0.0254 |
| TP | 6×50 mL | 300 | 1580 | 6.75 | 0.0064 |
| ALB | 6×50 mL | 300 | 1320 | 6.75 | 0.0077 |
| TB | R1: 4×40 mL, R2: 2×20 mL | 200 | 710 | 9.00 | 0.0190 |
| DB | R1: 4×40 mL, R2: 2×20 mL | 200 | 710 | 9.00 | 0.0190 |
| PA | R1: 1×45 mL, R2: 1×15 mL | 60 | 240 | 16.20 | 0.1013 |
| CHE | R1: 4×40 mL, R2: 2×20 mL | 200 | 650 | 21.00 | 0.0485 |
| ADA | R1: 2×40 mL, R2: 2×20 mL | 120 | 400 | 36.00 | 0.1350 |
| 5′-NT | R1: 2×40 mL, R2: 2×20 mL | 120 | 400 | 45.00 | 0.1688 |
| MAO | 2×50 mL | 100 | 520 | 18.00 | 0.0519 |
| GLDH | R1: 2×60 mL, R2: 2×20 mL | 160 | 670 | 28.80 | 0.0645 |
| LAP | R1: 2×60 mL, R2: 2×20 mL | 160 | 670 | 28.80 | 0.0645 |
| CG | R1: 2×30 mL, R2: 1×20 mL | 80 | 320 | 102.00 | 0.4781 |
| AMM | R1: 2×55 mL, R2: 2×20 mL | 150 | 650 | 49.50 | 0.1142 |
| GR | R1: 2×55 mL, R2: 2×20 mL | 150 | 650 | 135.00 | 0.3115 |
| GPDA | R1: 2×60 mL, R2: 2×20 mL | 160 | 670 | 72.00 | 0.1612 |
Myocardial Enzyme
| Product | Packing | Total Volume (mL) | Tests/Kit | EXW Price (USD/kit) | EXW Price (USD/test) |
|---|---|---|---|---|---|
| LDH | R1: 4×40 mL, R2: 4×20 mL | 240 | 980 | 14.40 | 0.0220 |
| CK | R1: 4×40 mL, R2: 2×20 mL | 200 | 710 | 45.00 | 0.0951 |
| CK-MB (Immunoinhibition) | R1: 2×48 mL, R2: 2×12 mL | 120 | 420 | 72.00 | 0.2571 |
| HBDH | R1: 4×40 mL, R2: 4×20 mL | 240 | 980 | 16.20 | 0.0248 |
| LDH1 | R1: 2×60 mL, R2: 2×20 mL | 160 | 670 | 28.80 | 0.0645 |
| CK-MB (Immunoturbidimetric) | R1: 2×55 mL, R2: 2×20 mL | 150 | 650 | 337.50 | 0.7788 |
Renal Function
| Product | Packing | Total Volume (mL) | Tests/Kit | EXW Price (USD/kit) | EXW Price (USD/test) |
|---|---|---|---|---|---|
| CRE-E | R1: 4×45 mL, R2: 4×15 mL | 240 | 1000 | 72.00 | 0.1080 |
| BUN | R1: 4×40 mL, R2: 2×20 mL | 200 | 710 | 10.50 | 0.0222 |
| UA | R1: 4×40 mL, R2: 4×20 mL | 240 | 980 | 12.60 | 0.0193 |
| β2-MG | R1: 2×40 mL, R2: 2×10 mL | 100 | 350 | 75.00 | 0.3214 |
| CysC | R1: 2×40 mL, R2: 2×10 mL | 100 | 350 | 75.00 | 0.3214 |
| NAG | R1: 2×60 mL, R2: 2×20 mL | 160 | 670 | 48.00 | 0.1075 |
Glucose Metabolism
| Product | Packing | Total Volume (mL) | Tests/Kit | EXW Price (USD/kit) | EXW Price (USD/test) |
|---|---|---|---|---|---|
| GLU-HK | R1: 4×40 mL, R2: 4×20 mL | 240 | 980 | 14.40 | 0.0220 |
| GLU-OX | R1: 4×40 mL, R2: 4×20 mL | 240 | 980 | 10.08 | 0.0154 |
| FMN | R1: 4×40 mL, R2: 2×20 mL | 200 | 710 | 30.00 | 0.0634 |
| D3-H | R1: 2×40 mL, R1a: 2×5 mL, R2: 2×15 mL | 120 | 480 | 54.00 | 0.1688 |
| HbA1c | R1: 2×15 mL, R2a: 1×0.5 mL, R2b: 1×9.5 mL, Hemolyse: 2×50 mL | 40 | 148 | 42.00 | 0.4257 |
| LAC | 4×50 mL | 200 | 1050 | 48.00 | 0.0686 |
| GA | R1: 2×30 mL, R2: 1×15 mL | 75 | 265 | 180.00 | 1.0189 |
| NEFA | R1: 2×30 mL, R2: 1×15 mL | 75 | 240 | 78.75 | 0.4922 |
| SA | R1: 2×30 mL, R2: 1×20 mL | 80 | 340 | 60.00 | 0.2647 |
Blood Lipids & Cardiovascular
| Product | Packing | Total Volume (mL) | Tests/Kit | EXW Price (USD/kit) | EXW Price (USD/test) |
|---|---|---|---|---|---|
| TG | R1: 4×40 mL, R2: 4×20 mL | 240 | 980 | 23.40 | 0.0358 |
| TCH | R1: 4×40 mL, R2: 4×20 mL | 240 | 980 | 14.40 | 0.0220 |
| HDL-C | R1: 4×45 mL, R2: 4×15 mL | 240 | 770 | 54.00 | 0.1052 |
| LDL-C | R1: 4×45 mL, R2: 4×15 mL | 240 | 770 | 72.00 | 0.1403 |
| ApoA1 | R1: 1×45 mL, R2: 1×15 mL | 60 | 165 | 18.00 | 0.1636 |
| ApoB | R1: 1×45 mL, R2: 1×15 mL | 60 | 230 | 18.00 | 0.1174 |
| ApoE | R1: 1×45 mL, R2: 1×15 mL | 60 | 240 | 54.00 | 0.3375 |
| Lp(a) | R1: 4×40 mL, R2: 2×20 mL | 240 | 710 | 216.00 | 0.4563 |
| HCY | R1: 2×30 mL, R2: 1×9 mL | 69 | 170 | 103.50 | 0.9132 |
| ACE | 2×50 mL | 100 | 410 | 45.00 | 0.1646 |
| Lp-PLA2 | R1: 1×60 mL, R2a: 1×14.25 mL, R2b: 1×0.75 mL | 75 | 230 | 225.00 | 1.4674 |
| Myo | R1: 2×55 mL, R2: 2×20 mL | 150 | 670 | 225.00 | 0.5037 |
Trace Elements & Electrolytes
| Product | Packing | Total Volume (mL) | Tests/Kit | EXW Price (USD/kit) | EXW Price (USD/test) |
|---|---|---|---|---|---|
| Ca | 4×45 mL | 180 | 780 | 6.75 | 0.0130 |
| Mg | 4×45 mL | 180 | 940 | 7.56 | 0.0121 |
| P | R1: 4×40 mL, R2: 4×20 mL | 240 | 980 | 7.20 | 0.0110 |
| CO2 | 5×20 mL | 100 | 490 | 27.00 | 0.0827 |
| Fe | R1: 2×40 mL, R2: 2×20 mL | 120 | 480 | 11.70 | 0.0366 |
| Na | R1: 2×60 mL, R2: 2×20 mL | 160 | 670 | 48.00 | 0.1075 |
| K | R1: 2×60 mL, R2: 2×20 mL | 160 | 670 | 96.00 | 0.2149 |
| Cl | 5×40 mL | 200 | 1040 | 7.50 | 0.0108 |
| UIBC | R1: 2×60 mL, R2: 2×12 mL | 144 | 360 | 17.28 | 0.0720 |
Specific Protein & Rheumatism
| Product | Packing | Total Volume (mL) | Tests/Kit | EXW Price (USD/kit) | EXW Price (USD/test) |
|---|---|---|---|---|---|
| ASO | R1: 2×40 mL, R2: 2×10 mL | 100 | 350 | 82.50 | 0.3536 |
| RF | R1: 2×40 mL, R2: 2×10 mL | 100 | 350 | 75.00 | 0.3214 |
| CRP (Immunoturbidimetric) | R1: 12×12.9 mL, R2: 12×12.9 mL | 309.6 | 920 | 162.54 | 0.2650 |
| CRP (Latex-enhanced Immunoturbidimetric) | R1: 12×12.9 mL, R2: 12×12.9 mL | 309.6 | 920 | 255.42 | 0.4164 |
| mAlb | R1: 2×40 mL, R2: 2×10 mL | 100 | 410 | 39.00 | 0.1427 |
| CSF | 2×50 mL | 100 | 520 | 13.50 | 0.0389 |
| RBP | R1: 1×45 mL, R2: 1×15 mL | 60 | 210 | 63.00 | 0.4500 |
| C3 | R1: 1×45 mL, R2: 1×15 mL | 60 | 240 | 16.20 | 0.1013 |
| C4 | R1: 1×45 mL, R2: 1×15 mL | 60 | 240 | 16.20 | 0.1013 |
| IgA | R1: 1×45 mL, R2: 1×15 mL | 60 | 230 | 22.50 | 0.1467 |
| IgM | R1: 1×45 mL, R2: 1×15 mL | 60 | 240 | 18.00 | 0.1125 |
| IgG | R1: 1×45 mL, R2: 1×15 mL | 60 | 230 | 20.25 | 0.1321 |
| PG I | R1: 2×30 mL, R2: 2×6 mL | 72 | 170 | 216.00 | 1.9059 |
| PG II | R1: 2×30 mL, R2: 2×6 mL | 72 | 170 | 216.00 | 1.9059 |
| CCP | R1: 2×30 mL, R2: 1×20 mL | 80 | 320 | 360.00 | 1.6875 |
| Fer | R1: 2×60 mL, R2: 1×60 mL | 180 | 720 | 486.00 | 1.0125 |
| TRF | R1: 2×55 mL, R2: 2×20 mL | 150 | 650 | 67.50 | 0.1558 |
| Hs-CRP | R1: 2×60 mL, R2: 1×60 mL | 180 | 740 | 148.50 | 0.3010 |
Pancreatitis
| Product | Packing | Total Volume (mL) | Tests/Kit | EXW Price (USD/kit) | EXW Price (USD/test) |
|---|---|---|---|---|---|
| AMY | R1: 4×40 mL, R2: 2×20 mL | 200 | 950 | 84.00 | 0.1326 |
| Lps | R1: 2×40 mL, R2: 2×20 mL | 120 | 480 | 90.00 | 0.2813 |
Venous Thromboembolism & Coagulation
| Product | Packing | Total Volume (mL) | Tests/Kit | EXW Price (USD/kit) | EXW Price (USD/test) |
|---|---|---|---|---|---|
| D-Dimer | R1: 1×45 mL, R2: 1×15 mL | 60 | 240 | 162.00 | 1.0125 |
Cleaning Solutions
| Product | Packing | Total Volume | EXW Price (USD) | Note |
|---|---|---|---|---|
| Cleaning Solution | 1×2 L | 2 L | 27.00 | Six months for 800 tests |
| Acidic Cleaning Solution | 2×60 mL | 120 mL | 22.50 | One month |
| Alkaline Cleaning Solution | 2×60 mL | 120 mL | 22.50 | One month |
Calibrators
| Product | Packing | EXW Price (USD) |
|---|---|---|
| Single-test Calibrator | / | 7.50 |
| Composite Calibrator Serum (ALT, AST, ALB, TB, ALP, CHE, GGT, BUN, CRE-E, UA, LDH, CK, HBDH, TG, GLU-HK, GLU-OX, AMY, LAP, GDH, Apo A1, Apo B, D3-H, IgA, IgM, IgG, UIBC) | 1×3 mL | 12.00 |
| Lipid Compound Calibrator (HDL-C, LDL-C, TG, TCH) | 1×1 mL | 10.50 |
Controls
| Product | Packing | EXW Price (USD) |
|---|---|---|
| Single-test Control | / | 7.50 |
| Composite Quality Control Serum (ALT, AST, ALB, TB, ALP, CHE, GGT, BUN, CRE-E, UA, LDH, CK, HBDH, TG, GLU-HK, GLU-OX, AMY, LAP, GDH, Apo A1, Apo B, D3-H, IgA, IgM, IgG, UIBC) | 1×3 mL | 12.00 |
| Lipid Compound Control (HDL-C, LDL-C, TG, TCH, Apo A1, Apo B) | 1×1 mL | 10.50 |
Spare Parts & Optional ISE Module
| Product | Description | EXW Price (USD) | Note |
|---|---|---|---|
| Computer | / | 900.00 | For CM400 & CM800 |
| ISE Module (for CM 400, 480 & 800) | ISE Module | 3,450.00 | / |
| Na+ Electrodes | 300.00 | / | |
| K+ Electrodes | 300.00 | / | |
| Cl- Electrodes | 300.00 | / | |
| Li+ Electrodes | 345.00 | / | |
| Reference Electrode | 300.00 | / | |
| Na+/K+/Cl-/Li+ Reagents | 330.00 | 1800 tests for each | |
| ISE Control | 150.00 | 3×1 level×10 mL | |
| ISE Module Cleaning Solution | 105.00 | 90 mL |
Product Specifications
| Specification | Detail |
|---|---|
| Model / SKU | GHM CM-430 US |
| Product Type | Fully Automated Open-System Clinical Chemistry Analyzer |
| Intended Use | Quantitative determination of biochemical parameters in serum, plasma, whole blood, urine, and cerebrospinal fluid; professional in vitro diagnostic use |
| System Configuration | Open system; user-programmable parameters for third-party and in-house reagents |
| Throughput | Constant 400 T/H (photometric); optional ISE module 400 T/H |
| Test Principles | Latex immunoturbidimetry, immunoturbidimetry, colorimetry |
| Test Methods | Rate method, end point method, fixed-time method |
| Sample Tray | 90 sample positions |
| Reagent Tray | 80 reagent positions; Peltier cooling |
| Simultaneous Test Items | Up to 78 chemistry items |
| Cuvettes | Glass reaction cuvettes (permanent use option) |
| Reaction Temperature | Direct dry heating, (37.0 ± 0.2)°C constant temperature control |
| Washing System | 8-step warm liquid washing; whole-probe stereo cleaning |
| Cross-Contamination Rate | < 0.01% |
| Mixing System | Upgraded mechanics (one stirrer less) for reduced maintenance |
| Sample Volume | 1.50–50.0 µL |
| Reagent Volume | R1: 10.0–450.0 µL; R2/R3/R4: 0 or 10.0–450.0 µL |
| Reaction Volume | 100.0–360.0 µL |
| Minimum Sampling Volume | 1.5 µL |
| Sample Types | Serum, plasma, whole blood, urine, cerebrospinal fluid |
| Optical System | Diffraction grating; 16 wavelengths |
| Calibration | Multi-point calibration curve (up to 7 points) |
| Dilution | Automatic pre-dilution |
| Water Consumption | ≤ 15 L purified water per hour |
| Dimensions | 1160 mm (L) × 790 mm (W) × 1140 mm (H) |
| Gross Weight | 300 kg |
| Regulatory Status | Manufactured under EN ISO 13485 certified quality management system |
Why Clinical Laboratories Choose Global Healthcare Medical
| Consideration | GHM CM-430 US |
|---|---|
| Open system flexibility | Program third-party or in-house reagents; avoid vendor lock-in |
| High throughput | Constant 400 T/H photometric; optional 400 T/H ISE |
| Extensive capacity | 90 sample positions; 80 reagent positions; up to 78 simultaneous items |
| Direct dry heating | (37.0 ± 0.2)°C precision without water bath maintenance |
| Multi-layer sampling safeguards | Polished probes, bubble detection, probe-clot detection |
| 8-step warm washing | Cross-contamination < 0.01% |
| Intelligent online loading | Reagents loaded during testing to reduce downtime |
| Advanced optics | Diffraction grating, 16 wavelengths |
| Cost-effective mechanics | Upgraded design (one stirrer less) reduces maintenance |
| ISO 13485 certified | Quality management system compliance |
About Global Healthcare Medical
Global Healthcare Medical is dedicated to connecting clinical laboratories and diagnostic centers with high-performance analytical systems designed for reliable operation in demanding healthcare environments. The GHM CM-430 US is part of our professional clinical chemistry line, developed to support accurate, efficient, and scalable testing in medium-to-high volume laboratory settings.
Our focus is on dependable analytical performance, clear documentation, and responsive support for professional clinical operations.
