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Global Healthcare Medical

GHM Human Metapneumovirus (HMPV) Antigen Rapid Test US – Qualitative Detection of Human Metapneumovirus Antigen with 8-Minute Results, Nasal / Nasopharyngeal Swab Sample Compatibility, and Professional Point-of-Care Use

GHM Human Metapneumovirus (HMPV) Antigen Rapid Test US – Qualitative Detection of Human Metapneumovirus Antigen with 8-Minute Results, Nasal / Nasopharyngeal Swab Sample Compatibility, and Professional Point-of-Care Use

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SKU: GHM Human Metapneumovirus (HMPV) Antigen Rapid Test US
Brand: Global Healthcare Medical

Product Overview

Global Healthcare Medical GHM Human Metapneumovirus (HMPV) Antigen Rapid Test US is a lateral flow immunochromatographic assay designed for the qualitative detection of human metapneumovirus (HMPV) antigen directly from human nasal or nasopharyngeal swab specimens. The kit is intended for use by healthcare professionals as an aid in the diagnosis of HMPV respiratory infection in symptomatic individuals.

Human metapneumovirus (hMPV) is a significant respiratory pathogen belonging to the Pneumoviridae family, primarily impacting young, elderly, and immunocompromised populations. Clinical presentations are similar to those of other respiratory viruses such as respiratory syncytial virus (RSV), influenza, and SARS-CoV-2, and can still lead to serious complications including bronchiolitis, pneumonia, and asthma or COPD exacerbations. A comprehensive review published in 2025 reported a 6.24% infection rate in hospitalized patients presenting with acute respiratory infections (ARIs), and estimated 473,000 hMPV-associated hospitalizations globally. In 2018, up to 14.2 million cases of hMPV were reported in children aged under 5 years worldwide, resulting in 7,700 in-hospital deaths. Given the morbidity and mortality rates of hMPV, which are comparable to those of influenza and RSV, enhanced surveillance and prevention are essential.

Because reinfection is common and symptoms overlap with RSV and influenza, rapid antigen-based detection plays a key role in differential diagnosis. Rapid hMPV testing enables clinicians to identify viral etiology at the point of care, avoid unnecessary antibiotic prescriptions, improve patient counseling and follow-up decisions, and reduce referrals and additional diagnostic testing. The GHM HMPV Antigen Rapid Test US delivers qualitative results in just 8 minutes, supporting rapid clinical decision-making at the point of care. The test is compatible with both nasal and nasopharyngeal swab specimens, providing flexible sample collection options suitable for a wide range of clinical settings.

The kit is intended for in vitro diagnostic use and professional use only, suitable for application scenarios including pediatric clinics, physician office laboratories, urgent care centers, emergency departments, hospital laboratories, and clinical laboratories. The VivaDiag product line is manufactured under an EN ISO 13485 certified quality management system covering in vitro diagnostic test kits and analyzers based on immunochromatography.

Key Features & Benefits

Colloidal Gold Immunochromatography – Reliable Qualitative Detection

The GHM HMPV Antigen Rapid Test US is based on lateral flow immunochromatography technology. The test incorporates monoclonal antibodies specific for Human Metapneumovirus antigen conjugated to visible labeling particles, detecting both major hMPV genotypes (A and B). During testing, the extracted swab specimen reacts with the antibody-coated particles and migrates up the membrane to react with the antibodies on the membrane. A colored line is generated at the test line region if HMPV antigen is present in the specimen.



Feature Benefit
Colloidal gold immunochromatography Established and reliable detection method
HMPV-specific monoclonal antibodies Targeted detection of HMPV nucleocapsid protein antigen
Detects both major hMPV genotypes (A and B) Comprehensive coverage of circulating hMPV strains
Qualitative visual result Clear and interpretable test outcome
No equipment required Simple and efficient testing workflow

Fast Results – 8 Minutes

The GHM HMPV Antigen Rapid Test US provides qualitative results in just 8 minutes, supporting rapid clinical decision-making and efficient patient workflow in point-of-care settings.



Feature Benefit
8-minute test time Rapid turnaround for timely clinical decisions
Point-of-care compatibility Suitable for pediatric clinics and physician offices
Efficient workflow Enables immediate patient assessment
Quick sample-to-result Supports high-throughput testing environments

Nasal / Nasopharyngeal Swab Compatibility – Flexible Sample Collection

The GHM HMPV Antigen Rapid Test US is compatible with both nasal and nasopharyngeal swab specimens, providing flexible sample collection options to accommodate different clinical protocols and patient needs. Optimized for early-stage infection, the test detects viral antigen at the point when hMPV viral load is typically highest and clinical symptoms are most pronounced.



Feature Benefit
Nasal / nasopharyngeal swab Flexible sample collection options
Simple procedure Convenient for routine testing
Multiple specimen types acceptable Adaptable to different clinical protocols
No special equipment required Streamlined workflow in clinical settings

Clinical Utility – Aid for Diagnosis of HMPV Respiratory Infection

The GHM HMPV Antigen Rapid Test US is intended for use as an aid in the diagnosis of HMPV respiratory infection. Antigen testing is most effective during the acute phase of respiratory illness, when symptoms often resemble the common cold, RSV, or influenza. The test provides rapid etiological diagnosis, enabling timely clinical decision-making and supporting infection control measures.

The test is particularly valuable for pediatric, geriatric, and immunocompromised patient populations, where hMPV infections are more prevalent and can be clinically severe. Early identification of HMPV infection supports appropriate patient management, reduces unnecessary antibiotic use, and helps limit hospitalizations. As no direct antiviral therapy for hMPV currently exists, rapid confirmation of hMPV can help avoid unnecessary empirical antibiotic therapy and repeated diagnostic workups in children, thereby improving patient management.



Feature Benefit
Active infection detection aid Supports identification of current HMPV infection
Early symptomatic phase utility Optimized for the acute phase of respiratory infection
Differential diagnosis support Helps distinguish HMPV from RSV, influenza, and other viral causes
Pediatric relevance Particularly useful in pediatric clinical settings
Geriatric relevance Valuable for older adult patient populations
Antibiotic stewardship support Helps reduce unnecessary empirical antibiotic use
Infection control support Enables prompt isolation and cohorting decisions
Clinical versatility Useful across pediatric clinics, physician offices, and emergency settings

High Accuracy – Trusted Clinical Performance

The GHM HMPV Antigen Rapid Test US is designed to deliver reliable clinical performance with high sensitivity and specificity. Clinical evaluation against PCR methods has demonstrated high relative sensitivity, specificity, and overall accuracy, making this assay a reliable frontline diagnostic tool for routine respiratory testing and outbreak settings.



Parameter Specification
Sensitivity 92.0%
Specificity 100%
Accuracy 96.3%
Limit of Detection Genotype A: 4.5 × 10³ TCID₅₀/mL; Genotype B: 3.0 × 10³ TCID₅₀/mL
Cross-reactivity No cross-reactivity observed with common respiratory viruses, including Influenza A/B, RSV, Adenovirus, Rhinovirus, or seasonal human coronaviruses

Performance characteristics based on PCR comparison studies of rapid hMPV antigen assays. Detection is optimal in specimens with high viral loads (Ct < 28), where positive agreement reaches 100%.

ISO 13485 Certified – Quality and Safety Compliance

The VivaDiag product line is manufactured under an EN ISO 13485 certified quality management system, demonstrating compliance with stringent international standards for the design, development, manufacture, and distribution of in vitro diagnostic test kits and analyzers.



Feature Benefit
EN ISO 13485 certification Quality management system compliance
IVD scope Certified for in vitro diagnostic test kits
Quality assurance Meets high standards of quality and safety
Professional-grade Designed for healthcare professional use

CE Marked – European Conformity

The GHM HMPV Antigen Rapid Test US is CE marked for professional in vitro diagnostic use, demonstrating conformity with applicable European regulatory requirements for diagnostic medical devices.



Feature Benefit
CE marking Regulatory compliance for professional use
Professional IVD use Designed for trained healthcare personnel
Quality compliance Meets European regulatory standards

Product Specifications



Specification Detail
Model / SKU GHM Human Metapneumovirus (HMPV) Antigen Rapid Test US
Product Code HMPV-502b
Product Type Human Metapneumovirus (HMPV) Antigen Rapid Test (Colloidal Gold)
Intended Use Qualitative detection of human metapneumovirus (HMPV) antigen directly from human nasal or nasopharyngeal swab specimens; used as an aid in the diagnosis of HMPV respiratory infection
Detection Principle Lateral flow immunochromatography; colloidal gold immunoassay
Target Antigen HMPV nucleocapsid protein antigen
Specimen Nasal swab / Nasopharyngeal swab
Time to Result 8 minutes
Sensitivity 92.0%
Specificity 100%
Accuracy 96.3%
Limit of Detection Genotype A: 4.5 × 10³ TCID₅₀/mL; Genotype B: 3.0 × 10³ TCID₅₀/mL
Storage Temperature 2–30°C
Shelf Life 24 months
Application Scenario Pediatric clinic, physician office laboratory, urgent care center, emergency department, hospital laboratory, clinical laboratory, point-of-care
Regulatory Status Manufactured under EN ISO 13485 certified quality management system; CE marked
Intended User Professional healthcare use only
Kit Size 25 tests/kit
Kit Contents Test Cassette, Extraction Buffer Tube, Disposable Swab, Instructions for Use

Why Clinical Professionals Choose Global Healthcare Medical



Consideration GHM Human Metapneumovirus (HMPV) Antigen Rapid Test US
Colloidal gold immunochromatography Established and reliable detection technology
8-minute test time Rapid turnaround for timely clinical decisions
Nasal / nasopharyngeal swab compatibility Flexible and convenient sampling options
HMPV nucleocapsid protein-specific detection Targeted detection of HMPV antigen
Detects both major hMPV genotypes (A and B) Comprehensive coverage of circulating strains
High sensitivity and specificity 92.0% sensitivity and 100% specificity
100% positive agreement at high viral loads Optimal performance in acute-phase specimens (Ct < 28)
No cross-reactivity No cross-reactivity with common respiratory viruses
Pediatric relevance Particularly valuable in pediatric clinical settings
Geriatric relevance Valuable for older adult patient populations
Antibiotic stewardship support Helps reduce unnecessary empirical antibiotic use
ISO 13485 certified Quality management system compliance
CE marked Regulatory compliance for professional use
Point-of-care compatible Suitable for pediatric clinics, physician offices, and emergency departments

About Global Healthcare Medical

Global Healthcare Medical is dedicated to connecting healthcare providers, retailers, and distributors with high-quality medical devices designed for reliable performance. The GHM Human Metapneumovirus (HMPV) Antigen Rapid Test US is part of our professional diagnostic line, developed to support accurate, efficient, and accessible point-of-care testing in clinical environments.

Our focus is on dependable performance, clear documentation, and responsive support for professional healthcare settings.

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